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KMID : 0363220110490070610
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Korean Journal of Dermatology
2011 Volume.49 No. 7 p.610 ~ p.613
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Kaposi’s Sarcoma in a Patient with Iatrogenic Cushing`s Syndrome
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Baek Yoo-Sang
Shin Won-Woong
Oh Tae-Seok
Son Soo-Bin
Song Hae-Jun
Oh Chil-Hwan
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Abstract
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Kaposi’s sarcoma (KS) is a multifocal proliferative vascular tumor involving cutaneous and extra-cutaneous tissues.
KS has been reported in patients treated with immunosuppressive agents for autoimmune diseases. However, KS has rarely been reported in patients with iatrogenic Cushing’s syndrome. A 77-year-old woman was evaluated with multiple asymptomatic violaceous nodules and plaques on both lower legs. She had been diagnosed with iatrogenic
Cushing’s syndrome and had been treated with low-dose corticosteroid replacement therapy for ＞10 years. A
histopathologic study showed extensive vascular proliferation in the dermis with spindle-shaped cells. Immunohistochemical staining for CD31, CD34, human herpesvirus (HHV)-8, and D2-40 was positive. We hereby report a case of KS in a patient with iatrogenic Cushing’s syndrome.
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KEYWORD
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Iatrogenic Cushing`s syndrome, Kaposi`s sarcoma
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